This book addresses nutrition, environmental factors, and advanced interventions from a multidisciplinary health perspective. It provides a detailed analysis of the negative effects of endocrine disruptors on fertility, advanced pharmacotherapy, surgery, and personalized management approaches in pediatric obesity, as well as the roles of sleep, stress, eating behaviors, and digital interventions. The molecular and clinical impacts of endocrine disruptors on both female and male fertility are discussed with scientific evidence. The treatment of pediatric obesity focuses on novel drugs, metabolic/bariatric surgery, and phenotype-based personalized therapy. The significance of sleep quality, psychosocial stress, and eating patterns in treatment success is emphasized, alongside the role of digital health technologies in improving access, continuity, and patient monitoring. Furthermore, the book explores the increasing consumption of ultra-processed foods among school-aged children and examines its societal determinants, including socioeconomic status, family influence, and media advertising, alongside the multifaceted adverse health outcomes. The book aims to provide interdisciplinary solutions to the complex health issues arising from the intertwined nature of dietary habits, environmental exposures, and advanced interventions.