This academic work provides a multidisciplinary examination of architecture through the lenses of digital transformation, urban change, building sciences, and sustainability. The first chapter investigates the impact of artificial intelligence on creative freedom and autonomy in architecture, critically engaging with philosophical theories by Heidegger and Feenberg regarding technology’s influence on design processes. Subsequent sections address spatial design dynamics, transformation of neighborhood relations amid urbanization, and the integration of urban lighting with circadian health principles. Using fuzzy logic, the sustainability of traditional houses in Sivrihisar is assessed concerning environmental adaptability. The book also explores off-site production methods and the role of digital manufacturing and 3D printing in improving construction industry productivity. Further, it highlights the implementation of open-source, IFC-based semantic data management in Building Information Modeling (BIM) for enhanced material property integration. The final chapter focuses on historical thermal structures, analyzing their architectural meaning from physical and mental experience perspectives across ancient, Roman, and Ottoman periods. Through a combination of theoretical discussion, computational techniques, and case studies, the volume comprehensively examines architecture’s evolving practices and the integration of technology with heritage and sustainability considerations.